Studi / Pubblicazioni

Pubblicazioni soci AIFEG

 

2017

Roncucci L, Pedroni M, Mariani F.

Attenuated adenomatous polyposis of the large bowel: Present and future.

World J Gastroenterol. 2017 Jun 21;23(23):4135-4139. doi: 10.3748/wjg.v23.i23.4135.

 

Vogelaar IP, van der Post RS, van Krieken JHJ, Spruijt L, van Zelst-Stams WA, Kets CM, Lubinski J, Jakubowska A, Teodorczyk U, Aalfs CM, van Hest LP, Pinheiro H, Oliveira C, Jhangiani SN, Muzny DM, Gibbs RA, Lupski JR, de Ligt J, Vissers LELM, Hoischen A, Gilissen C, van de Vorst M, Goeman JJ, Schackert HK, Ranzani GN, Molinaro V, Gómez García EB, Hes FJ, Holinski-Feder E, Genuardi M, Ausems MGEM, Sijmons RH, Wagner A, van der Kolk LE, Bjørnevoll I, Høberg-Vetti H, van Kessel AG, Kuiper RP, Ligtenberg MJL, Hoogerbrugge N.

Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing.

Eur J Hum Genet. 2017 Sep 6. doi: 10.1038/ejhg.2017.138. [Epub ahead of print]

 

Marabelli M, Gismondi V, Ricci MT, Vetro A, Abou Khouzam R, Rea V, Vitellaro M, Zuffardi O, Varesco L, Ranzani GN.

A novel APC promoter 1B deletion shows a founder effect in Italian patients with classical familial adenomatous polyposis phenotype.

Genes Chromosomes Cancer. 2017 Aug 9. doi: 10.1002/gcc.22488. [Epub ahead of print]

 

Feroce I, Serrano D, Biffi R, Andreoni B, Galimberti V, Sonzogni A, Bottiglieri L, Botteri E, Trovato C, Marabelli M, Ranzani GN, Bonanni B.

Hereditary diffuse gastric cancer in two families: A case report.

Oncol Lett. 2017 Aug;14(2):1671-1674. doi: 10.3892/ol.2017.6354. Epub 2017 Jun 8.

 

Procaccio L, Schirripa M, Fassan M, Vecchione L, Bergamo F, Prete AA, Intini R, Manai C, Dadduzio V, Boscolo A, Zagonel V, Lonardi S.

Immunotherapy in Gastrointestinal Cancers.

Biomed Res Int. 2017;2017:4346576. doi: 10.1155/2017/4346576. Epub 2017 Jul 3. Review.

 

Galuppini F, Pennelli G, Loupakis F, Lanza C, Vianello L, Sacchi D, Mescoli C, Salmaso R, Agostini M, Lonardi S, Farinati F, Rugge M, Fassan M.

BRAF p.V600E-specific immunohistochemical assessment in colorectal cancer endoscopy biopsies is consistent with the mutational profiling.

Histopathology. 2017 Jul 19. doi: 10.1111/his.13315. [Epub ahead of print]

 

Abou Khouzam R, Molinari C, Salvi S, Marabelli M, Molinaro V, Orioli D, Saragoni L, Morgagni P, Calistri D, Ranzani GN.

Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer.

Oncotarget. 2017 Mar 21;8(12):18811-18820. doi: 10.18632/oncotarget.13401.

 

Viel A, Bruselles A, Meccia E, Fornasarig M, Quaia M, Canzonieri V, Policicchio E, Urso ED, Agostini M, Genuardi M, Lucci-Cordisco E, Venesio T, Martayan A, Diodoro MG, Sanchez-Mete L, Stigliano V, Mazzei F, Grasso F, Giuliani A, Baiocchi M, Maestro R, Giannini G, Tartaglia M, Alexandrov LB, Bignami M.

A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.

EBioMedicine. 2017 Jun;20:39-49. doi: 10.1016/j.ebiom.2017.04.022. Epub 2017 Apr 13.

 

Carnevali I, Libera L, Chiaravalli A, Sahnane N, Furlan D, Viel A, Cini G, Cimetti L, Rossi T, Formenti G, Ghezzi F, Riva C, Sessa F, Tibiletti MG.

Somatic Testing on Gynecological Cancers Improve the Identification of Lynch Syndrome.

Int J Gynecol Cancer. 2017 May 2. doi: 10.1097/IGC.0000000000001010. [Epub ahead of print]

 

Libera L, Sahnane N, Carnevali IW, Cimetti L, Cerutti R, Chiaravalli AM, Riva C, Tibiletti MG, Sessa F, Furlan D.

Microsatellite analysis of sporadic and hereditary gynaecological cancer in routine diagnostics.

J Clin Pathol. 2017 Apr 17. pii: jclinpath-2017-204348. doi: 10.1136/jclinpath-2017-204348. [Epub ahead of print]

 

Mariani F, Boarino V, Bertani A, Merighi A, Pedroni M, Rossi G, Mancini S, Sena P, Benatti P, Roncucci L.

Myeloperoxidase-positive cell infiltration of normal colorectal mucosa is related to body fatness and is predictive of adenoma occurrence.

Int J Obes (Lond). 2017 Jun;41(6):982-985. doi: 10.1038/ijo.2017.80. Epub 2017 Mar 30.

 

de Leon MP, Pedroni M, Roncucci L, Domati F, Rossi G, Magnani G, Pezzi A, Fante R, Bonetti LR.

Attenuated polyposis of the large bowel: a morphologic and molecular approach.

Fam Cancer. 2017 Apr;16(2):211-220. doi: 10.1007/s10689-016-9938-9.

 

Furlan D, Trapani D, Berrino E, Debernardi C, Panero M, Libera L, Sahnane N, Riva C, Tibiletti MG, Sessa F, Sapino A, Venesio T.

Oxidative DNA damage induces hypomethylation in a compromised base excision repair colorectal tumourigenesis.

Br J Cancer. 2017 Mar 14;116(6):793-801. doi: 10.1038/bjc.2017.9.

 

Mancini S, Mariani F, Sena P, Benincasa M, Roncucci L.

Myeloperoxidase expression in human colonic mucosa is related to systemic oxidative balance in healthy subjects.

Redox Rep. 2017 Jan 9:1-9. doi: 10.1080/13510002.2016.1277049. [Epub ahead of print]

 

Ricci MT, Miccoli S, Turchetti D, Bondavalli D, Viel A, Quaia M, Giacomini E, Gismondi V, Sanchez-Mete L, Stigliano V, Martayan A, Mazzei F, Bignami M, Bonelli L, Varesco L.

Type and frequency of MUTYH variants in Italian patients with suspected MAP: a retrospective multicenter study.

J Hum Genet. 2017 Feb;62(2):309-315. doi: 10.1038/jhg.2016.132

 

Scarpa A, Chang DK, Nones K, Corbo V, Patch AM, Bailey P, Lawlor RT, Johns AL, Miller DK, Mafficini A, Rusev B, Scardoni M, Antonello D, Barbi S, Sikora KO, Cingarlini S, Vicentini C, McKay S, Quinn MC, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, McLean S, Nourse C, Nourbakhsh E, Wilson PJ, Anderson MJ, Fink JL, Newell F, Waddell N, Holmes O, Kazakoff SH, Leonard C, Wood S, Xu Q, Nagaraj SH, Amato E, Dalai I, Bersani S, Cataldo I, Dei Tos AP, Capelli P, Davì MV, Landoni L, Malpaga A, Miotto M, Whitehall VL, Leggett BA, Harris JL, Harris J, Jones MD, Humphris J, Chantrill LA, Chin V, Nagrial AM, Pajic M, Scarlett CJ, Pinho A, Rooman I, Toon C, Wu J, Pinese M, Cowley M, Barbour A, Mawson A, Humphrey ES, Colvin EK, Chou A, Lovell JA, Jamieson NB, Duthie F, Gingras MC, Fisher WE, Dagg RA, Lau LM, Lee M, Pickett HA, Reddel RR, Samra JS, Kench JG, Merrett ND, Epari K, Nguyen NQ, Zeps N, Falconi M, Simbolo M, Butturini G, Van Buren G, Partelli S, Fassan M; Australian Pancreatic Cancer Genome Initiative., Khanna KK, Gill AJ, Wheeler DA, Gibbs RA, Musgrove EA, Bassi C, Tortora G, Pederzoli P, Pearson JV, Waddell N, Biankin AV, Grimmond SM.

Whole-genome landscape of pancreatic neuroendocrine tumours.

Nature. 2017 Mar 2;543(7643):65-71. doi: 10.1038/nature21063.

 

Smyth EC, Wotherspoon A, Peckitt C, Gonzalez D, Hulkki-Wilson S, Eltahir Z, Fassan M, Rugge M, Valeri N, Okines A, Hewish M, Allum W, Stenning S, Nankivell M, Langley R, Cunningham D.

Mismatch Repair Deficiency, Microsatellite Instability, and Survival : An Exploratory Analysis of the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) Trial.

JAMA Oncol. 2017 Feb 23. doi: 10.1001/jamaoncol.2016.6762. [Epub ahead of print]

 

 

2016

 

Abou Khouzam R, Molinari C, Salvi S, Marabelli M, Molinaro V, Orioli D, Saragoni L, Morgagni P, Calistri D, Ranzani GN.

Digital PCR identifies changes in CDH1 (E-cadherin) transcription pattern in intestinal-type gastric cancer.

Oncotarget. 2016 Nov 16. doi: 10.18632/oncotarget.13401. [Epub ahead of print]

 

Bellan A, Cappellesso R, Lo Mele M, Peraro L, Balsamo L, Lanza C, Fassan M, Rugge M.

Early signet ring cell carcinoma arising from colonic adenoma: the molecular profiling supports the adenoma-carcinoma sequence.

Hum Pathol. 2016 Apr;50:183-6. doi: 10.1016/j.humpath.2015.12.006.

 

Carnevali IW, Cimetti L, Sahnane N, Libera L, Cavallero A, Formenti G, Riva C, Tibiletti MG.

Two Cases of Carcinosarcomas of the Ovary Involved in Hereditary Cancer Syndromes.

Int J Gynecol Pathol. 2016 May 10. [Epub ahead of print]

 

Chiappa A, Bertani E, Zbar AP, Foschi D, Fazio N, Zampino M, Belluco C, Orsi F, Della Vigna P, Bonomo G, Venturino M, Ferrari C, Biffi R.

Optimizing treatment of hepatic metastases from colorectal cancer: Resection or resection plus ablation?

Int J Oncol. 2016 Mar;48(3):1280-9. doi: 10.3892/ijo.2016.3324.

 

Corbellini C, Biffi R, Luca F, Chiappa A, Costa S, Bertani E, Bona S, Lombardi D, Tamayo D, Botteri E, Andreoni B.

Open, laparoscopic, and robotic surgery for rectal cancer: medium-term comparative outcomes from a multicenter study.

Tumori. 2016 Aug 3;102(4):414-21. doi: 10.5301/tj.5000533.

 

La Rosa S, Bernasconi B, Frattini M, Tibiletti MG, Molinari F, Furlan D, Sahnane N, Vanoli A, Albarello L, Zhang L, Notohara K, Casnedi S, Chenard MP, Adsay V, Asioli S, Capella C, Sessa F.

TP53 alterations in pancreatic acinar cell carcinoma: new insights into the molecular pathology of this rare cancer.

Virchows Arch. 2016 Mar;468(3):289-96. doi: 10.1007/s00428-015-1882-9.

 

Marabelli M, Molinaro V, Khouzam RA, Berrino E, Panero M, Balsamo A, Venesio T, Ranzani GN.

Colorectal Adenomatous Polyposis: Heterogeneity of Susceptibility Gene Mutations and Phenotypes in a Cohort of Italian Patients.

Genet Test Mol Biomarkers. 2016 Dec;20(12):777-785. doi: 10.1089/gtmb.2016.0198.

 

Sahnane N, Bernasconi B, Carnevali I, Furlan D, Viel A, Sessa F, Tibiletti MG.

Disruption of the APC gene by t(5;7) translocation in a Turcot family.

Cancer Genet. 2016 Mar;209(3):107-11. doi: 10.1016/j.cancergen.2015.12.003.

 

Saraggi D, Fassan M, Mescoli C, Scarpa M, Valeri N, Michielan A, D’Incá R, Rugge M.

The molecular landscape of colitis-associated carcinogenesis.

Dig Liver Dis. 2016 Dec 21. pii: S1590-8658(16)30831-3. doi: 10.1016/j.dld.2016.12.011. [Epub ahead of print]

 

 

2015

 

Cini G, Carnevali I, Quaia M, Chiaravalli AM, Sala P, Giacomini E, Maestro R, Tibiletti MG, Viel A.

Concomitant mutation and epimutation of the MLH1 gene in a Lynch syndrome family.

Carcinogenesis. 2015 Apr;36(4):452-8. doi: 10.1093/carcin/bgv015.

 

Quadri M, Vetro A, Gismondi V, Marabelli M, Bertario L, Sala P, Varesco L, Zuffardi O, Ranzani GN.

APC rearrangements in familial adenomatous polyposis: heterogeneity of deletion lengths and breakpoint sequences underlies similar phenotypes.

Fam Cancer. 2015 Mar;14(1):41-9. doi: 10.1007/s10689-014-9750-3.

 

Roncucci L, Mariani F.

Prevention of colorectal cancer: How many tools do we have in our basket?

Eur J Intern Med. 2015 Dec;26(10):752-6. doi: 10.1016/j.ejim.2015.08.019. Review.

 

Sena P, Mariani F, Mancini S, Benincasa M, Magnani G, Pedroni M, Palumbo C, Roncucci L.

Autophagy is upregulated during colorectal carcinogenesis, and in DNA microsatellite stable carcinomas.

Oncol Rep. 2015 Dec;34(6):3222-30.

 

Simbolo M, Mafficini A, Agostini M, Pedrazzani C, Bedin C, Urso ED, Nitti D, Turri G, Scardoni M, Fassan M, Scarpa A.

Next-generation sequencing for genetic testing of familial colorectal cancer syndromes.

Hered Cancer Clin Pract. 2015 Aug 21;13(1):18. doi: 10.1186/s13053-015-0039-9.

 

Tricarico R, Cortellino S, Riccio A, Jagmohan-Changur S, Van der Klift H, Wijnen J, Turner D, Ventura A, Rovella V, Percesepe A, Lucci-Cordisco E, Radice P, Bertario L, Pedroni M, Ponz de Leon M, Mancuso P, Devarajan K, Cai KQ, Klein-Szanto AJ, Neri G, Møller P, Viel A, Genuardi M, Fodde R, Bellacosa A.

Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis.

Oncotarget. 2015 Dec 15;6(40):42892-904. doi: 10.18632/oncotarget.5740.

 

Studi collaborativi AIFEG

 

Remo A, Fassan M, Lanza G.

Immunohistochemical evaluation of mismatch repair proteins in colorectal carcinoma: the AIFEG/GIPAD proposal.

Pathologica. 2016 Sep;108(3):104-109.

 

Sahnane N, Magnoli F, Bernasconi B, Tibiletti MG, Romualdi C, Pedroni M, Ponz de Leon M, Magnani G, Reggiani-Bonetti L, Bertario L, Signoroni S, Capella C, Sessa F, Furlan D; AIFEG..

Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.

Clin Epigenetics. 2015 Dec 21;7:131. doi: 10.1186/s13148-015-0165-2.

 

Resta N, Pierannunzio D, Lenato GM, Stella A, Capocaccia R, Bagnulo R, Lastella P, Susca FC, Bozzao C, Loconte DC, Sabbà C, Urso E, Sala P, Fornasarig M, Grammatico P, Piepoli A, Host C, Turchetti D, Viel A, Memo L, Giunti L, Stigliano V, Varesco L, Bertario L, Genuardi M, Lucci Cordisco E, Tibiletti MG, Di Gregorio C, Andriulli A, Ponz de Leon M; AIFEG.

Cancer risk associated with STK11/LKB1 germline mutations in Peutz-Jeghers syndrome patients: results of an Italian multicenter study.

Dig Liver Dis. 2013 Jul;45(7):606-11.

 

Marroni F, Pastrello C, Benatti P, Torrini M, Barana D, Cordisco EL, Viel A, Mareni C, Oliani C, Genuardi M, Bailey-Wilson JE, Ponz de Leon M, Presciuttini S.

A genetic model for determining MSH2 and MLH1 carrier probabilities based on family history and tumor microsatellite instability.

Clin Genet. 2006 Mar;69(3):254-62.

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